Two Mississippians were killed Monday afternoon when their car collided with an semi-truck; two others were seriously injured in the wreck.

Mississippi Highway Patrol troopers said the wreck happened at approximately 2:15 p.m. on Highway 309 South in Marshall County near the Watson community.

Rekeem T. Ingram of Byhalia was driving with his mother, Dorothy Ingram, when their car struck the back end of the truck.

Both Ingrams were killed in the crash. Two others were seriously injured and had to be airlifted to a hospital.

The cause of the wreck is under investigation.